80 research outputs found

    Results from the testing and analysis of LDEF batteries

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    Batteries were used on the Long Duration Exposure Facility (LDEF) to provide power to both the active experiments and the experiment support equipment such as the Experiment Initiative System, Experiment Power and Data System (data acquisition system), and the Environment Exposure Control Canisters. Three different types of batteries were used: lithium sulfur dioxide (LiSO2), lithium carbon monofluoride (LiCF), and nickel cadmium (NiCd). A total of 92 LiSO2, 10 LiCF, and 1 NiCd batteries were flown on the LDEF. In addition, approximately 20 LiSO2 batteries were kept in cold storage at NASA LaRC. The various investigations and post-flight analyses of the flight and control batteries are reviewed. The primary objectives of these studies was to identify degradation modes (if any) of the batteries and to provide information useful to future spacecraft missions. Systems SIG involvement in the post-flight evaluation of LDEF batteries was two-fold: (1) to fund SAFT (original manufacturer of the LiSO2 batteries) to perform characterization of 13 LiSO2 batteries (10 flight and 3 control batteries); and (2) to integrate investigator results

    Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

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    Genome-wide characterization of the in vivo cellular response to perturbation is fundamental to understanding how cells survive stress. Identifying the proteins and pathways perturbed by small molecules affects biology and medicine by revealing the mechanisms of drug action. We used a yeast chemogenomics platform that quantifies the requirement for each gene for resistance to a compound in vivo to profile 3250 small molecules in a systematic and unbiased manner. We identified 317 compounds that specifically perturb the function of 121 genes and characterized the mechanism of specific compounds. Global analysis revealed that the cellular response to small molecules is limited and described by a network of 45 major chemogenomic signatures. Our results provide a resource for the discovery of functional interactions among genes, chemicals, and biological processes

    On Uniformly Sampling Traces of a Transition System (Extended Version)

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    A key problem in constrained random verification (CRV) concerns generation of input stimuli that result in good coverage of the system's runs in targeted corners of its behavior space. Existing CRV solutions however provide no formal guarantees on the distribution of the system's runs. In this paper, we take a first step towards solving this problem. We present an algorithm based on Algebraic Decision Diagrams for sampling bounded traces (i.e. sequences of states) of a sequential circuit with provable uniformity (or bias) guarantees, while satisfying given constraints. We have implemented our algorithm in a tool called TraceSampler. Extensive experiments show that TraceSampler outperforms alternative approaches that provide similar uniformity guarantees.Comment: Extended version of paper that will appear in proceedings of International Conference on Computer-Aided Design (ICCAD '20); changed wrong text color in sec 7; added 'extended version

    The N2K Consortium. I. A Hot Saturn Planet Orbiting HD 88133

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    The N2K ("next 2000") consortium is carrying out a distributed observing campaign with the Keck, Magellan, and Subaru telescopes, as well as the automatic photometric telescopes of Fairborn Observatory, in order to search for short-period gas giant planets around metal-rich stars. We have established a reservoir of more than 14,000 main-sequence and subgiant stars closer than 110 pc, brighter than V = 10.5, and with 0.4 0.1 dex for this survey. We outline the strategy and report the detection of a planet orbiting the metal-rich G5 IV star HD 88133 with a period of 3.41 days, semivelocity amplitude K = 35.7 m s^(-1), and M sin i = 0.29M_J. Photometric observations reveal that HD 88133 is constant on the 3.415 day radial velocity period to a limit of 0.0005 mag. Despite a transit probability of 19.5%, our photometry rules out the shallow transits predicted by the large stellar radius

    Navigating Gender at Sea

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    Fieldwork, including work done at sea, is a key component of many geoscientists' careers. Recent studies have highlighted the pervasive harassment faced by women and LGBTQ+ people during fieldwork. However, transgender and gender diverse (TGD) scientists face obstacles which have not yet been thoroughly examined. We fill this gap by sharing our experiences as TGD people. We have experienced sexual harassment, misconduct, privacy issues, and legal and medical struggles as we conduct seagoing work. In this work, we provide recommendations for individuals, cruise leaders, and institutions for making seagoing work safer for our communities
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